Hi Yahia,
I found this from the Natural Standards database:
"Apple (Malus domestica) are considered to be a safe part of the human diet. They are thought to be an effective treatment for diarrhea in children, high blood cholesterol, hair growth, burn wounds, allergies, mercury poisoning, and the side effects of radiation. Some studies suggest that apples may help slow cancer development, manage diabetes, and help patients prepare for surgery."
http://www.naturalstandard.com/databases/herbssupplements/patient-apple.asp?
Level of evidence C (unclear or conflicting)
Evidence of benefit from >1 small RCT(s) without adequate size, power, statistical significance, or quality of design by objective criteria,* OR conflicting evidence from multiple RCTs without a clear majority of the properly conducted trials showing evidence of benefit or ineffectiveness, OR evidence of benefit from >1 cohort/case-control/non-randomized trials AND without supporting evidence in basic science, animal studies, or theory, OR evidence of efficacy only from basic science, animal studies, or theory.
And of course coriander
Did not find anything relevant for lead in this database
Good luck!
I think that herbs like plantago ovata or other herbs with geling agents, which may have absorptive properties agains heavy metals are able for the bonding of mercury or lead. But it depend on the kind or on the form the metals appeare.
It may be possible to ligate mercury or lead in the lower intestine through the fatty acids, which are evolved by microbes when you take resistent starches of the type R3. Also herbs with high amounts of tannins, humic acid or fulvic acid may be able to fix the metals.
I suggest to point your search on plants containing high quantity of phytochelatins, a family of peptides containing SH groups which are known to bind several metals and also mercury.
For example you may take a look at the following article:
Complexation of Hg with phytochelatins is important for plant Hg tolerance
Carrasco-Gil, Sandra; Alvarez-Fernandez, Ana; Sobrino-Plata, Juan; Millan, Rocio; Carpena-Ruiz, Ramon O.; Leduc, Danika L.; Andrews, Joy C.; Abadia, Javier; Hernandez, Luis E.
Plant, Cell and Environment (2011), 34(5), 778-791.
Wormwood- Artemisia absinthium L may have a protective effect on lead
"Neuroprotective effect of wormwood against lead exposure"
O Kharoubi, M Slimani, and A Aoues J Emerg Trauma Shock. 2011 Jan-Mar; 4(1): 82–88.
doi: 10.4103/0974-2700.76834
"These data suggest that wormwood extract may play a very useful role in reduction of the neurotoxicological damage induced by lead.
Keywords: Acetylcholinesterase, behavioral test, brain region, lead acetate, lipid peroxidation, monoamine oxidase "
full text here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097587/
Here's full-text relating to your question http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485653/
Metallothionein is an endogenous compound which chelates heavy metals. The gene coding for Metallothionein is expressed when the transcription factor Nrf2 is activated. The naturally-occurring compound with the most potent known ability to activate Nrf2 is sulforaphane, derived from the Brassica genus and in particular from 100% whole broccoli sprouts but not extracts of the sprouts. Read more on this subject here: www.ncbi.nlm.nih.gov/pubmed/16033772
Now this paper is officially published and also this one may be of interest for your research:
Properties of dihydroasparagusic acid and its use as an antidote against mercury(II) poisoning
Armandodoriano Bianco, Emilio Bottari, Maria Rosa Festa, Lorella Gentile, Anna Maria Serrilli, Alessandro Venditti
Monatshefte für Chemie 10/2013; DOI:DOI: 10.1007/s00706-013-1095-3
Regards,
AV
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