So, basically, I am trying to see if cell is differentiating(gross changes in chromatin structure accompany cellular differentiation) based on the nuclei images,
and I got a few different ways of condensations.
Case 1. This I presumed might relate to differentiation. you could find small holes uniformly distributed.
Case 2. a big hole in the center.
Case 3. more than one hole
Case 4. brain??
These are typical morphologies of nuclei that I observed
Can you share your expertise on this?? I would be very appreciated!