Yes, you can use mouse for the study of prostate cancer. You can also use testosterone to induce prostate cancer in rats. I used it to induce BPH.
Pls see the below reference link and the attached pdf:
Pamela J. Russell, Dale J. Voeks. Animal Models of Prostate Cancer. In Prostate Cancer Methods and Protocols. Methods in Molecular Medicine, Volume 81, 2003, pp 89-112.
You can use PC-3 or DU-145 human prostate cancer cells orthotopically grafted into the prostate of immunocompromized mice as detailed in the attached article.
Best regards
Robert
PS for Alok: if you read my response to Priyanka, could you send me an e-mail at [email protected]?