cefpodoxime is BCS IV class drug so I am trying to enhance its solubility. but I am not able to understand that from which part of GIT it is absorbed.
You need to check whether cefpodoxime proxetil belongs to weak acidic or weak basic drugs. Generally, weak acidic and weak basic drugs are more soluble in basic and acidic medium, respectively.
I have modelled an Concrete gravity dam subjected to Under water explosion by Coupled acoustic structural technique. In the result section, I got an acoustic pressure vs time graph. I want to know...
16 May 2024 8,159 0 View
In my current research, I am investigating the characterization of bacteria capable of degrading crude oil. The quantify the crude oil degrading ability of the bacteria, the existing protocol...
11 April 2024 6,685 3 View
I use the phenomenological model for the crystal plasticity simulations, where the shear strain can be taken as output. However, I require the shear strain rate on individual slip planes to...
08 March 2024 648 1 View
We want to use past data for historical reference point.
28 November 2023 2,169 2 View
I have simulated the stress-controlled cyclic loading in DAMASK. However, I am having difficulty setting up the load-case file for strain-controlled cyclic loading between two given strain levels.
19 October 2023 9,771 1 View
2. In forest ecology studies, for which types of samples or datasets is the Margalef diversity index most applicable? Are there specific scenarios where it is particularly informative? 3. When...
12 October 2023 7,527 0 View
Dear all, I have the following data and questions related to the issues in the results. Independent variable I did an online survey and asked parents questions about neighbourhood-built...
26 September 2023 4,919 4 View
The CAD detector is not working properly. Could someone explain why that be the case? or the ways to try to troubleshoot it.
17 September 2023 770 1 View
I have been researching about bacterial isolation from petroleum\crude oil contaminated soil samples. While reading the papers, I seem to notice that everyone has a different approach for...
13 August 2023 3,806 0 View
I am trying to understand it in relation to novel bacterial discovery. I want to understand other approaches (other than traditional isolation techniques) that can be utilized to screen for...
06 August 2023 8,882 1 View
I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...
07 August 2024 2,282 2 View
..
05 August 2024 4,406 0 View
I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...
03 August 2024 4,724 2 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
Hello everyone, I am try to understand the differences interaction between insoluble and soluble polymers in water with metal ions and how theit charge density (of metal ions) affect the interaction.
29 July 2024 6,350 3 View
Dear all: I am modifying Bismuth Tungstate with Hematite (Fe2O3), so I would like to know about how much Iron(+3) can form a solid solution in a Bismuth Oxide matrix. Best wishes Marco
29 July 2024 2,161 1 View
I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...
24 July 2024 8,695 0 View
I was performing estimation of Total Soluble Sugar content in bacterial cultures by Anthrone method. Out of 9 samples, only one sample showed positive reading while others had a negative reading...
22 July 2024 9,576 4 View
Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...
19 July 2024 2,155 0 View
How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...
15 July 2024 4,191 1 View