Can SIRT2/6-IN-1 be used in animal experiments?

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Hello everyone, may I ask what the dosage of SIRT2/6-IN-1 (HY-123194, MCE) is for intraperitoneal injection in rats? We have read many references but were unable to find the exact dosage for rats.

Wang Ting Ting

Hi,

There are very few literature reports on this product currently. We have not found any literature on its administration in rats, but we have identified relevant studies in mice, which you may refer to. Generally, based on dosage conversion, the dosage for rats is 1/2 of that for mice; however, dosages may vary depending on the experimental model, so it is recommended to explore both high and low dosage groups.

PMID: 35150745

The answer to this question is provided by MedChemExpress Technical Support. [email protected]

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