Can high carbohydrate ingestion lead to diffusional problems around the sarcolemma due to increased subsarcolemmal glycogen granules?
Can it lead to storage of glucose in the form of glycogen which would be less functional and cause diffusional problems around the sarcolemma, or lead to specific concentration gradient, which would blunt normal muscle cell functioning?
Can isolated glycogen granules occur in the sarcoplasm which are less functional, and while they lead to increase of muscle cell volume (form of hypertrophy) they are less functional?
Can there be an increase in amount of granules, and/or would you expect glycogen granules to be filled in more tiers, or not?
Hello peter
I think your question can explain with chemistry science. We know that capacity of muscle and liver glycogen are limit for storage of glucose in glycogen form. However the exercise can increase this capacity for certain level but yet is limit this capacity. on the other hand when someone follow the high carbohydrate diet, excess amount of carbohydrate by insulin turn into the triglyceride and storage in adipocyte cells. We know that insulin level change after the ingestion carbohydrate and availability of glucose. However exercise and metabolic stress can change some metabolic pathway and I think we must consider the level and type of the exercise. For more find out, I propose study the book of “biochemistry for sport and exercise metabolism” by Donald MacLaren and James Morton.
good luck
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