I have been helping with a study looking at obesity. its a multiple timepoint study, so each patient should have 4 serums, baseline, 1 month, 3 months and 6 months. I have been processing the latter part of the study blood samples after another colleague left for a new job. As I was sorting the serums from the PBMCs to be sent for analysis, I saw that some of the labelling for the first half of the study serums weren't lining up with the spreadsheet I was given.
Myself and the clinical fellow running the study went through the mis labelled serums and re labelled the tubes on the assumption the date was correct and therefore what he had on his clinical calendar. However, although I was really trying to help as the fellow was obviously annoyed and frustrated this had happened (not at anyone in particular, just things like this occasionally happen), my science brain was very much 'this is really not good practice and we're making a lot of assumptions that I wouldn't be comfortable with).
He asked if there is any way to match up the mislabelled serums to the other serums for that patient we know are correct? I've seen a few articles about circulating DNA for biomarkers and such, but would these be sufficient to tell us if our assumptions on which serum belongs to which patient is correct?
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