Dear Surendra

Chlorpyrifos solubility in various solvents including:

Solubility of Chlorpyrifos

In water, 1.4 mg/L at 25 deg C

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Chlorpyrifos (2921-88-2) (2008-2010)

In water, 1.12 mg/L at 24 deg C

Yalkowsky, S.H., He, Yan, Jain, P. Handbook of Aqueous Solubility Data Second Edition. CRC Press, Boca Raton, FL 2010, p. 586

In water, 0.39 mg/L at 19.5 deg C /OECD 105 method/

World Health Org; WHO Specifications and Evaluations for Public Health Pesticides. Chlorpyrifos (March 2009). Available from, as of April 2: 2014:http://www.who.int/whopes/quality/Chlorpyrifos_WHO_specs_eval_Mar_2009.pdf

Solubility at 25 deg C: isooctane 79% wt/wt; methanol 43% wt/wt

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Cambridge, UK: Royal Society of Chemistry, 2013., p. 390

Solubility (g/100 g): acetone 650, benzene 790, carbon disulfide 590, carbon tetrachloride 310, chloroform 630, diethyl ether 510, ethanol 63, ethyl acetate >200, isooctane 79, kerosene 60, methanol 45, methylene chloride 400, propylene glycol 4, toluene 150, 1,1,1-trichloroethane 400, triethylene glycol 5, xylene 400. Readily soluble in other organic solvents.

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Cambridge, UK: Royal Society of Chemistry, 2013., p. 390

Solubility in water, mg/l at 25°C: 1.4 (very poor)

0.0002%

Also have a look at this Guidelines:

Hello Surendra, As i have worked on Chlorpyrifos, i have dissolved it in acetone for the degradation studies. Also check the data sheet for more info.

Thanks