Can anyone refer me any article of Median Lethal Dose(MLD)/LD50 of Naja kaouthia venom?

More Ankur Das Barma's questions See All

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

Do you mix and add all primers together in a singel PCR reaction (4 total primers for 2 mutations) when using Agilent's multi-site mutagenesis kit?

I want to introduce 2 mutations using Agilent's multi-site mutagenesis kit, I designed the primers using their online tool and it gave me 2 sets for primers (1 set for each mutation) so I was...

25 July 2024 6,517 3 View

How can we identify (in silico) the interacting amino acid residues or the nucleotides involved in the Protein-Protein / Protein-RNA interaction?

Hello! everyone, I am trying to study in silico Protein-Protein and Protein-RNA interactions. Now, is there any tool with which I can identify the interacting amino acid residues or the...

14 July 2024 950 2 View

Any suitable Animal models to evaluate Mast cell stabilizers?

I am looking for an in-vivo model to evaluate standardized herbal extract for its potential as a mast cell stabilizer.

14 July 2024 779 0 View

What is the mathematical expressionof theoretical yield strength calculated considering solution strengthening in stainless steel 316L?

In the expression for solid solution strengthening model that has been widely used in the literature use a linear form consisting of strength coefficient, and concentration of elements in wt.%....

11 July 2024 4,476 3 View

How to insert cholesterol inside DPPC membrane by replacing same number of DPPC molecules in GROMACS?

I am trying to insert cholesterol inside the DPPC membrane by using gmx insert_molecules -replace. But number of DPPC molecules replaced is much higher than the number of cholesterol inserted?...

30 June 2024 4,160 2 View

How to synthesize Dichloro(p-cymene)ruthenium(II) dimer in a good yield?

Suggest some procedure where i can synthesize [Ru(p-cymene)Cl2]2 in a good yield.

23 June 2024 9,244 2 View

Analysis of microbial biomass for nutrient cycling?

It will be an honor, if anyone can suggest the standard methodology for analyzing nutrients(N,P,K) in soil microbial biomass

23 June 2024 3,850 4 View

Can i use polystyrene as a matrix in a hybrid COMPOSITE?

fiber powders will be used as a reinforcement.

23 June 2024 10,027 3 View

After expert validation of the research tool for data collection, what should be done first after piloting. Reliability analysis or factor analysis?

Which would be prefered first (factor analysis or reliability analysis of a Likert type scale)

19 June 2024 9,378 4 View

Which MWCO filter to use to get rid of unwanted proteins?

I am working with snake venom, specifically targeting toxins around the 15 kDa range. I need to remove higher molecular weight toxins (above 20 kDa). Would it be advisable to use a 20 kDa MWCO...

05 June 2024 691 1 View

Is it recommended to use 3×10^10 bacterial cells to cause systemic infection?

I am using female BALB/c mice (6-8 weeks old, 23-25g weight) for the testing of a phage cocktail. Initially, I determined Minimum Lethal Dose (MLD) of my bacterial strain (S.aureus isolated from...

18 May 2024 6,095 1 View

Does the Primer3 design primers for the COBRA technique? and selecton of single Restriction enzyme for multiple genes?

Hello, RG Members, I have designed the COBRA primers using the UCSC genome browser for the promoter regions of genes of my intreset. are these primers reliable? I have tried the other softwares...

17 April 2024 7,882 0 View

According to your experience which is better to use hard or soft bite plates for TMDs management??

Bite plate type for TMDs.

10 April 2024 8,982 0 View

Has anyone observed an injury caused by a spiny dogfish sting resulting in isolated muscle atrophy in human?

Fisherman stung while extracting hook from fish.

19 March 2024 535 0 View

Are there any Apitherapy or apipuncture protocols for bee venom injection or bee stings??

I'm looking for apipuncture protocols for bee venom injection or bee stings practicing. I appreciate it very much if you can share what you have.

23 October 2023 6,936 0 View

Potential of combining bee venom with castor oil ?

Dear colleagues, I am an enthusiastic practitioner of Apitherapy, actively searching for established protocols regarding the utilization of honeybee hive products in a general context....

18 October 2023 7,026 0 View

How can I calculate the number of animals and groups I need in animal research?

My study aims at developing an animal model for type II diabetes. I don’t quite understand the power calculation, particularly in regards to the values I would substitute into the equation, as it...

23 September 2023 421 3 View

How to choose STZ dosage groups for chemically-induced diabetes in mice?

My research aims to produce a novel mouse model for T2DM and I have two dosage techniques to administer STZ in C57BL/6 mice: single high dose (SHD) and multiple low dose (MLD). Within these...

11 September 2023 671 3 View

Does anybody has LC-MS Vipera berus venom chromatogram?

I am looking for LC-MS spectrum of the common adder Vipera berus with or without identification of individual peaks to compare with my results.

17 August 2023 5,877 1 View

Russell G A Jones

The following paper with iv LD50s for Naja kaouthia venom and purified neurotoxin should help.

Article Experimental evaluation of ovine antisera to Thai cobra (Naj...

Marshall D Mccue

Here are two good (old but good) books the present large tables of the LD50 of different venoms from a broad range of species:

Brown, J. H. (1973). Toxicology and Pharmacology of Venoms from Poisonous Snakes. Springfield, Charles C. Thomas.

Tu, A. T. (1977). Venoms: Chemistry and Molecular Biology. New York, John Wiley & Sons.