Can anyone list the tools/tool for making PSSM matrix

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Critical micelle concentration (CMC) for DOPE and DOPG?

I am working on membrane systems comprising of DOPE and DOPG in the ratio 3:1. It would be very helpful for me, if you have any information about the CMC for DOPE as well as the same for DOPG. Any...

07 August 2017 7,653 3 View

Is there a way to narrow down the docked conformation list before applying molecular dynamics?

I have docked ~100 molecules using Surflex-Dock as well as AutoDock and prepared two lists (one for each docking program) based on their scores and energies. I have narrowed the list by...

31 December 2015 8,869 10 View

Is multi core calculation/simulation possible in AutoDock (v4) module?

Autodock is widely accepted program to perform small molecule docking. Unfortunately, this program uses a single core, while other core of the machine remains idle. This way, we are not able to...

10 November 2015 8,470 4 View

How to find out free energy of protein-ligand system, using 'g_energy' module of gromacs ?

There is an option of using PLUMED along with MD simulation (via gromacs) to interpret the free energy of a given system. But, in case we want to directly access the free energy from energy output...

05 June 2015 4,246 2 View

Is there any server online to predict a mature sequence from a given protein sequence?

I have in hand, a protein sequence of Cystein protease of an organism (325 amino acid residues). From that sequence, I need only a mature sequence. I wanted to know, is there any online server to...

31 December 2013 7,346 5 View

Can a journal be banned if it doesn't review publications before publishing, but charges publication fees?

Most of the journals are excellent in content, but nowadays, some people have started a business to publish papers in their journal, without paying attention to the content after the author pays...

10 November 2013 9,882 8 View

Where can I get the list of the top 10 Biological Journals in terms of Impact Factor?

I need updated information, regarding the impact factors of Top Journals in market.

03 April 2013 6,107 3 View

What is the biological significance of Higher A, G, C, T count, respectively?

We are familiar with the fact that A binds with T, G binds with C. And also we know that high GC contents illustrate that the DNA is more stable, and temperature tolerable. But I want to know,...

02 March 2013 793 0 View

What would happen if polycomb group proteins (PcGs) were mutated?

We are familiar with the fact that polycomb response elements play a crucial role in helping the PcGs to silence a particular expression. This is saved in the memory of the cell, and carried out...

01 February 2013 6,338 0 View

Which are/is the best, freely available, user friendly Software for plotting a graph for systems biology simulation or any other simulation?

Plotting of graphs are the best means for the analysis of our results. But if they are plotted wrong, then surely we can conclude wrong results. Many of the biologists are not very familiar to...

11 December 2012 4,430 5 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,101 4 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,770 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,429 2 View

Which Scopus Journal provides the most affordable fees?

"PUBLISHING IN A SCOPUS JOURNAL" Researchers are now at a cross road. The critical need to publish in a Scopus or ISI, etc journal is ever vital. Journal Publication fees must be submitted....

10 August 2024 8,621 1 View

Seeking Advice on Viability and Execution of Undergraduate Thesis Topic?

Hello everyone, I am currently developing a thesis proposal and would appreciate your input on its viability and how to effectively carry it out. My proposed topic is: "Does the perceived threat...

10 August 2024 8,992 0 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

Who will be moral responsible for the death of thousands of people in the event of an earthquake?

Who will bear moral responsibility for the deaths of thousands of people in the event of an earthquake? Weeks and months remain before the onset of strong earthquakes that bring death to...

08 August 2024 6,134 12 View

How are iso-frequency contours plotted?

Let's say we have a standard, regular hexagonal honeycomb with a 3-arm primitive unit cell (something like the figure attached; the figure is only representative and not drawn to scale). The...

07 August 2024 1,937 1 View