15 Questions 131 Answers 0 Followers
Questions related from Pedro A Reche
I am interested in assembling a file with the sequences of the most highly expressed proteins in humans. Are these proteins available somewhere?
07 July 2017 5,839 4 View
Impact points have disappeared from Researchgate. Hard to understand this downgrade . Please, get them back. It was a helpful metric that one could not get that easily anywhere else.
04 April 2017 10,040 1 View
I am looking at B-factors in two different PDB protein structures and I wonder if these B-factors are suitable for direct inter-PDBs comparisons, say to tell whether a particular loop in protein...
05 May 2016 7,292 4 View
I am getting negative branches with the Neighbor-joining method, which I set to zero. However, I've read that I should transfer negative distances somewhere else and I do not know how. Does...
02 February 2015 7,867 3 View
Does anyone know of any antibody that could bind to IL7RA and block signaling? Thanks in advance for any help.
01 January 2015 5,826 2 View
When available I report the journal impact factor of my articles corresponding to the year that the articles were published. However, I wonder if there is a consensus for choosing the year of the...
10 October 2014 6,001 4 View
Diet and microbiota are two intertwined factors that could act as environmental triggers of systemic autoimmune diseases. Both diet and microbiota are likely to be similar between spouses and I...
04 April 2014 6,724 12 View
I am trying to align a sequence to a multiple sequence alignment obtained from an 3D-structural alignment (superimposed 3D structures). The sequence is related to the sequences in the multiple...
05 May 2013 333 16 View
We need synthetic peptides for Elispot assays and we wonder from which company to get them. We have found that ChinaPeptides offer peptide synthesis at very competitive prices. However, we have...
04 April 2013 4,262 2 View
ClustalX has an option to obtain bootstrap neighbor joining trees from an alignment. However, the trees differ considerably from those one can get using bootstrapping with the phylip package...
01 January 2013 2,209 14 View
I am interested in isolating effector T cells from peripheral blood. Does anyone know any recipe/kit or have any recommendation?
10 October 2012 9,434 9 View
I understand Th1/Th2 T cell polarization occurs in secondary lymphoid organs (e.g. lymphatic nodules), where T cells recognized the antigens in the presence of different signals that condition...
09 September 2012 2,474 18 View
I would like to know for IAV, HIV and HCV the copy number of each of the proteins assembling these mature viruses. Any help/reference answering the question will be greatly appreciated.
06 June 2012 1,963 4 View
We are having here a discussion over a scientific topic and I thought I can get here the help to settle it. The diversity of the immunoglobulins is generated by stochastic rearrangement of...
04 April 2012 3,630 12 View
FcgRII-I is an inhibitory receptor expressed in both naive and memory B cells. However, in naive B cells, this receptor prevent the response against antigens for which there are preformed...
04 April 2012 6,408 4 View