In a human heart according to the increase in the developmental stage, the heart tissue stiffness (Extra cellular matrix stiffness) goes on increasing. Has anyone checked the human heart tissue stiffness? Can anyone give some ideas about it?
Dear Ravindra,
A sensitive method for detecting Heart stiffness is by assessing stress-strain relationships. Utilizing pressure-volume relationships, the elastic stiffness may be evaluated in patients with normal ventricles, inappropriate hypertrophy, and congestive cardiomyopathy
Thanks Anil for your valuable answer. Is there any data suggesting what is the exact stiffness (Modulus of elasticity) in normal and hypertrophic ventricles in human?
Ravindra,
You probably find hundreds of papers on this issue if you search the keyword: diastolic dysfunction.
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