Can anybody suggest which is the best area to do clinical translation in regenerative medicine or stem cell therapy?

31 December 2013 1 3K Report

I would like to do clinical translational research in animal models later on human trials please suggest proven area especially in regenerative medicine or dentistry.

Charan Thej

Hi,

Since you are into dental sciences,may be you can start the work with dental pulp stem cells.They are multipotent but yet have a propensity for the ectodermal lineage and this you can try it for neurological diseases.

Regards

Charan

Badges
Science topic

More Sunil Pm's questions See All

What does the disappearance of the XRD peak near 8 degrees, corresponding to the (002) plane of MXene, imply in a MXene-based nanocomposite?

I am trying to synthesize Mxene based nanocomposites. Interestingly, the characteritic peak dissapears which indicates the disruption in interlayer spacing of MXene. So, what might be other...

03 July 2024 5,702 3 View

How to prepare polyaniline emeraldine salt ( PANI -ES) sample for Transmission electron microscope (TEM) analysis?

I need to do TEM analysis for my Polyaniline emeraldine salt form. May I know which solvent is appropriate for preparing TEM sample?

25 June 2024 9,086 3 View

How can soil health be maintained or improved in agricultural systems to ensure long-term productivity?

27 April 2024 3,920 1 View

How can farmers adapt to climate change and mitigate its effects on crop production?

27 April 2024 3,858 8 View

Cloud Computing based pantry system using IoT?

I am researcher doing my research related to this topic, This paper is published in 2021 IEEE conference proceedings, if any one have this paper - Kindly share this paper and help me for my research

13 April 2024 4,713 4 View

What to do if mean_squared_error is high while doing Gradient Boosting Regression?

While doing Gradient boosting regression, I am getting the following values for mean_squared_error:8401567843.246913 mean_absolute_percentage_error: 0.20303839201988907 Is the result valid if...

10 April 2024 6,730 1 View

Can artificial intelligence ever replicate the nuanced emotional intelligence inherent in natural intelligence?

06 April 2024 4,468 2 View

Role of artificial intelligence in vermicomposting?

27 March 2024 5,841 2 View

How do traditional agricultural knowledge and modern scientific understanding intersect in natural farming?

24 March 2024 396 2 View

How can ML algorithms be effectively applied to optimize recruitment processes in HRM, specifically resume screening and candidate shortlisting?

The integration of artificial intelligence and machine learning (AI/ML) in Human Resource Management (HRM) has the potential to revolutionize traditional talent acquisition practices. In this...

22 January 2024 8,177 2 View

What are the emerging trends and opportunities for STEM education and careers in the online space?

10 August 2024 507 0 View

Why Do TDS and EC Increase with Larger Wastewater Volumes, While BOD and COD Decrease?

I have carried out MFC experiments on three different volumes, 50, 500 and 1000 mL of wastewater. Results after MFC treatment shows that TDS and EC are more in larger volumes of water i.e. TDS and...

09 August 2024 9,621 0 View

Could it be a cell culture contamination?

Hello everyone! I observed in my culture (htert-RPE1 cells) an orange- red particle at the bottom of the dish. It is visible to the naked eye as a very very small red dot. Could it be a...

09 August 2024 2,824 3 View

Is there any way to quantify bacterial and fungal cells in their mixed culture?

I am working in fungal fermentation of soybean meal and there is bacterial growth in them at times. I am trying to quantify fungal cell counts and bacterial cells; but I haven't been able to do at...

07 August 2024 7,535 4 View

How to normalize and take the significance of the MTT OD values with 3 replicates for the same cell-line?

Hi, I have a question about normalizing the MTT OD values for doing the statistical analysis. So, if we have 3 different plates and we call them 3 different replicates, so, first we would...

07 August 2024 8,106 4 View

Why activated CAR-Jurkat cell could not kill targets?

Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...

06 August 2024 641 2 View

How much total RNA concentration to be extracted from sorted plasma cells from bone marrow of C57BL/6 mice for RT-PCR ?

i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...

05 August 2024 8,835 1 View

How to isolate lymphocytes from mouse spleen?

I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...

04 August 2024 9,913 7 View

How to Add Missing Water Molecules in Protein-Membrane Simulations?

I have protein-membrane simulations (PDB, PSF, DCD) and have noticed that water molecules near the protein are not visible in the simulations. How can I fix this issue? Is there a way to place the...

04 August 2024 1,200 2 View

How to use Density Functional Theory to calculate carrier mobilities of solid system?

Hello, everyone. I have tried to determine carrier motilities of some materials, by Density Functional Theory, using Quantum ESPRESSO. There are a few methods to do it, like a package called...

04 August 2024 8,894 1 View