I am trying to observe DNA fragmentation in HeLa cell lines, but every time i isolate DNA and run Agarose electrophoresis only thing i can see is smear.

I have used C-TAB method for isolating DNA fragments.

In the image of gel from left

Lane1: DNA ladder (1Kb)

Lane 2: Control untreated

Lane 3: test compound treated

Lane 4: H2O2 treated

 please suggest a good and tested method

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