I wish to understand whether it is possible to make a phonon mode resonate with an externally applied signal in a lab, and whether a laser can be used for the purpose (if not, is there any other source that will do the job?).
Dear Sourabh Lahiri , yes, it is indeed possible to couple a phonon mode with an electromagnetic wave, to create a sort of hybrid quasiparticle called polariton.
Rigorously speaking a polariton is a quantum superposition state between a photon and a matter excitation. The matter excitation can be a collective mode (a phonon) in solids or an electron in atoms or molecules.
https://en.wikipedia.org/wiki/Polariton
https://www.nature.com/subjects/polaritons
"Polaritons are hybrid particles made up of a photon strongly coupled to an electric dipole. Examples of such a dipole include an electron–hole pair in a semiconductor, which forms an exciton polariton, and the oscillating electrons at the surface of a metal, which creates a surface-plasmon polariton."
A good description of different polaritons can be found in the following article and review, please have a look to them: