I am working on a project in which we need to study the working memory of mice before and after treatment. I have tried using the 8-arm radial maze but the mice are not at all interested in the food even after 4-5 hours starving and so I have been unsuccessful in training them. I tried using a modified 8-arm maze with an arm open because initially the mice wanted to escape and it worked for a while but the mice seemed to have learned that there is no reward on escaping. Could anyone suggest a method that works with all strains of mice?
Open-field ambulation before and after maze learning was my PhD. There was no problem to motivate the mice also of different strains. I can attach a picture of our maze:
S. Béatrice Marianne Ewalds-Kvist I would really appreciate it if you could attach a picture of the maze
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