Once the professional organisation and the economic resources are fully adequate, the epidemiological unit of intervention should be defined. Whenever the collective prevalence (percentage of infected herds) in this unit be uniformly very low (always less than 1% of herds infected), a strategy based on a test and slaughter programme and a ban on vaccination could be applied to eradicate the disease in the short to medium term in that particular epidemiological unit. In the case where prevalence is uniformly moderate (less than 10%), a combined eradication programme based on the simultaneous application of vaccination in young replacements and a test and slaughter in adult animals could be recommended to eradicate the disease in the medium to long term. However, when the disease is highly prevalent (more than 10% of herds are infected), even though the professional organisation and the economic resources be fully adequate, the mass vaccination of all animals from all animal species involved in the epidemiological cycle is the only reasonable strategy that can be applied to control the disease. For success in the application of the last two strategies, the use of adequate vaccines and vaccination procedures is of paramount relevance
Vaccinate not only depends on the prevalence, also of the possibility of controlling trade in animals, farm biosecurity etc. If unable to perform them is more advisable to establish a vaccination program because the program test and sacrifice will fail
It depends on prevalence rate if low only test and slaughter and if high and endemic in area mass vaccination is suggested In India only mass vaccination and test and segregation is possible.