HI, Any body have synthesized aryl 1,3,4-oxadiazol-2-thiol derivative form an acid hdrazide and CS2/KOH? what is the sequence of additions? my acid hydrazide is insoluble in ethanol
Hi! Try to reflux acid hydrazide in EtOH/KOH solution, then after cooling of mixture add CS2.
You can also look through references from review
Majumdar P. et al. Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings //Chemical reviews. – 2014. – Т. 114. – №. 5. – С. 2942-2977.