The cause of depression has been established. Chronic depression leads to the list of consequences that you have listed. You can read about the main mechanism of depression in my article about depression on my page in RG. The cause and mechanism of depression have been established and all stages are clearly defined. Depression is very complex. Currently, depression is managed by trying to influence some symptoms of depression. Existing methods do not affect the main mechanism of depression. Therefore, depression and related symptoms are now free to develop. The harm from depression will constantly increase. Very serious consequences are possible. Suicides, neurodegenerative diseases - all these are consequences of chronic depression. Depression is now a very important human problem that must be solved quickly, otherwise the consequences can be very serious. The problem of understanding depression is very complex, since depression is based on a mechanism that is unknown to the general public. Therefore, the attitude to depression is now the same as to a natural disaster. Depression appears out of nowhere and behaves unpredictably. But if you know the cause and mechanism, then depression becomes a common disorder that can be eliminated by routine methods. The problem of depression is solved.

What causes depression? How can depression be prevented? Why is depression spreading freely now? Why do medications and psychotherapy not affect depression? Is it possible to trace all the stages of depression in detail? Is an attempt to adapt to depression a solution to the problem of depression? What methods can completely stop depression and is it possible? If you have depression, can it go away on its own or will you always be depressed? .............

Dear Vasil,

thank you for your thoughtful contribution. We agree that the complexity of depression calls for integrated, interdisciplinary approaches. Your focus on underlying mechanisms is thought-provoking and invites deeper scientific dialogue. I encourage you to consider submitting a manuscript to our Nursing Reports Special Issue on Mental Health in Later Life. Insights like yours can advance clinical understanding and inform policy. We welcome international collaboration and look forward to continued exchange.

Depression is an extremely complex disease. Special conditions are needed to make the solution to depression public. The processes of depression are currently unknown to the general public. Currently, all published literature on depression and that will be published in the near future is a set of some assumptions, the application of which in practice does not give a positive result in the treatment of depression plus side effects. If society needs a solution to depression and related diseases, then it should be more active in attracting researchers. The solution to depression is one of the main problems of society and every day of delay in solving the problem of depression will cause enormous harm to a person. Already now, depression and related diseases cause enormous harm to a person, which can be estimated at many hundreds of billions of Swiss francs (CNF). And over time, this harm will constantly increase.