Are there tissue-specific differences in the effects of telomerase activity on cell lifespan during aging? If so, what are the mechanisms?

05 November 2024 0 1K Report

Are there significant differences in telomerase activity in different tissues or cell types (e.g., skin, muscle, neurons, etc.)?

How do these differences affect the aging process of the tissue or cell?

What is the molecular mechanism of the difference in telomerase activity? Is it determined by gene expression regulation, epigenetic factors, or tissue-specific physiological needs?

Can telomerase activity be used as a potential therapeutic target in aging-related diseases (e.g., Alzheimer's disease, cardiovascular disease)?

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