A friend of mine, 54 year female, diabetic and hypertensive gets severe flare ups of psoriasis-at least 3-4 times a week. Due to past history of hepatotoxicity, she has given up on drugs and is using only topical oil applications. Are there any newer drugs that are safe and effective so that I could convince her to visit a dermatologist again?
Is a cure for psoriasis on the horizon?
Highly targeted antibody-based treatments have been game-changing for people with moderate to severe psoriasis — a painful skin condition that also comes with a high risk of developing cardiovascular diseases, diabetes and arthritis, and can take a toll on mental health. But these antibody therapies, which selectively take out the inflammatory molecules that drive the disease, have a major drawback: they must be taken for life. Or at least that’s what was thought. Now large clinical trials are trying to find out why some people who have to cease treatment for other reasons remain psoriasis-free...
https://www.nature.com/articles/d41586-025-02649-w
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