Are tacrolimus (HY-13756, MCE) and plerixafor (HY-10046, MCE) used together in combination? Are they injected into the same mouse, or administered separately into two different mice (i.e., as part of two distinct experimental models)?
Tacrolimus and Plerixafor:
Are the two products used in combination, and are they injected into the same mouse? Or are they injected into two mice separately and belong to two models?
Because DMSO and ethanol are toxic to a certain extent, generally for normal mice, the proportion is 10%, and 200μL is injected into a 20 g mouse. If it is a weak mouse, it is recommended to reduce the proportion of DMSO or ethanol to 2%.
For normal mice, the following are recommended:
1) Use the two drugs in combination, and it is recommended to inject 100 μL of each drug, or a little less.
2) Administer the drugs separately, and your original plan is feasible.
The answer to this question comes from MedChemExpress Technical Support.
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