02 September 2020 1 4K Report

Dear all,

I have a (slightly long) statistics / data science question concerning the applicability, implementation and concise reporting of a log-linear model.

I am also open for alternative suggestions.

Data:

We recorded activity of neurons in different brain regions, different cell types within these regions and using different stimuli. For each of these factors we get different numbers of neurons which we classify based on responsiveness criteria to belong to three groups.

So we have a multi-level contingency table with:

R1-3 = Response variable (3 level) - frequency

Several multilevel conditions:

stimulus type (S1-3), cell type (C1-2), brain region (B1-2).

My questions:

1. is a log-linear model the analysis of choice here - or am I completely off?

2. is my model selection and comparison reasonable?

3. is focusing on interaction only and disregarding main effects (which are trivial here based on random sampling over conditions) sound?

4. How should I report on model selection and interaction relevance in the most concise way possible (severe space limitations in publication)?

- - - - -

I chose to analyze this with a multifactorial log linear model and test for interactions (which may be incorrect - pls advice).

The independence model would be:

log(freq) = log(R) + log(S) + log(C) + log(B)

R:

mod0 |z|) = 0.01 **

R1:B1 - Pr(>|z|) = 0.1

Or should I report full statistics on individual model GOF (G2, df, coefficient estimates, individual p-values etc.)?

My questions (again)

1. is a log-linear model the analysis of choice here - or am I completely off?

2. is my model selection and comparison reasonable?

3. is focusing on interaction only and disregarding main effects (which are trivial here based on random sampling over conditions) sound?

4. How should I report on model selection and interaction relevance in the most concise way possible (severe space limitations in publication)?

Thanks!

T

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