I'd like to know the type of AAV and promoter and the best effective time on the rat skin. Any advice on the injection method would also be helpful. Thanks.
Hello, in a paper entitled "In vivo reprogramming of wound-resident cells generates skin epithelial tissue", it is mentioned that AAV is used for skin wound therapy. They also used subcutaneous injection of GFP-AAV and direct administration to compare the efficacy of different AAVs. Using GFP, they were able to observe the ability of tissue cells to become hosts for certain AAVs. Perhaps this information will provide you with some reference and inspiration. Thank you for reading.But I am sorry that I have not conducted any related experiments.Due to limitations in my knowledge, my responses also have many shortcomings. I hope you can get more accurate anwsers.