I am trying to understand the implication of some SNPs responsible for disease in cattle. I want to calculate and predict the risk of disease from risk allele of an SNP in an individual animal from odds ratio from the literature.
I have tried understanding " likelihood percentage", "population attributable risk" and "polygenic risk score" for single and multiple snps.
Can anyone suggest some parameters like above which are most suitably to predict the genetic risk?
Soumitra K Mallick
If you are running a controlled experiment over time and want to do impact assessment you have to try out some Bayesian Statistical Method with Genetic controls like "serendipity ratio".I hope this helps.SKM
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