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Questions related from Suresh Oncosuresh
Hi All. I am using 4 different plasmid, each encoding different scFv with similar back bone, The only difference between all the plasmid is nucleotide encoding for scFv seq (Antibody Seq)....
02 February 2019 2,144 12 View
Here is an example : concentration Average Percentage viability in normal cell line 0.1 1001 98.2310 ...
09 September 2016 8,684 4 View
1) Which one of the following has increased risk of becoming tumor ? A) Cells with shortest doubling time (often divide) and shortest life span. B) Cells with longest doubling time (rarely divide)...
06 June 2016 4,682 1 View
if there is any gene specific carcinogen (che,bio,phy),we can initiate gene alteration specifically to tumor and later we can develop drug for it ... Carcinogen , Gene alteration, targeted drug
06 June 2016 5,669 4 View
We all know that CSC (Cancer stem cell) are germ line of tumor giving rise to body of tumor cell. Then why this body of tumor cell fails to carry single gene mutation or single gene alteration,...
06 June 2016 9,220 3 View
Consider this scenario, where 35 year old female is diagnosed for breast cancer (malignant), her Breast tumor is completely dissected from her breast or body via mastectomy or lumpectomy. Later...
06 June 2016 1,928 6 View
During MTT assay, after seeding we unknowingly forget to cover 96 well plate with the given lid and we incubated for 24hr in 5% Co2, humidified with copper sulphate. After 24 hr of seeding, we...
04 April 2016 4,366 10 View
Here You go .. I was looking for answer ,can tumor arise from normal cell without genetic or epigenetic changes .. Answer is YES .. Here you Go...
07 July 2015 9,520 0 View
As we know well the genomic DNA is cleaved into nucleosomal sub units by CAD enzyme during Apoptosis .. If every part of genomic DNA is cleaved to 180bp (Nucleosomal sub unit) ,then how do we get...
09 September 2014 6,975 5 View
Will ALL acute lymphoblastic leukemia T lymphocyte/B lymphocytes protect themselves from foreign substances (Microbes) in cancer patients? If Yes, how will they do this? Being immature cells, how...
07 July 2014 3,815 5 View
Both beneficial and pathogenic organism might have similar MAMP ( microorganism associated molecular pattern) such as flagellin,LPS dsRNA.CpG etc .HOW do our Host cell TLR(Toll like receptor) can...
07 July 2014 5,798 8 View
Or any over grown cell line after reaching confluency using inverted microscope? Did anyone see foci in T25 flask with normal inverted microscope? I have read and saw the image in 'Biology of...
09 September 2013 7,323 2 View
We human migrate from one place to another, when we could not able to find the basic needs like water shelter, food. But why cancer cell has to migrate from its place of origin?We know how and...
09 September 2013 3,914 12 View
It is well known that Single mutant Proto Oncogene is not sufficient to initiate tumor /bring Biochemical and morphological charecterisitc associted with tumor such as foci formation,invasion etc...
09 September 2012 9,443 0 View
Can a tumor arise from differentiated cell ? (or) Can differentiated cell be reverted to undifferentiated /de differentiated ? Can a malignant be reverted to benign .. Please do let me know...
09 September 2012 5,948 0 View
Dendritic cell present antigenic peptide to CD4+Tcell or CTLs and activate them to kill tumor cell or viral infected cell ,which is specific to the antigen presented by Dendritic cell .. My...
10 October 2011 6,414 21 View
