R M Bazai

15 Questions 5 Answers 0 Followers

Questions related from R M Bazai

Method development of paracetamol oral suspension ?

Hi Dear Actually, i am trying to develop the related substances method for paracetamol oral suspension in RP HPLC and i am getting small peak in the diluent at the RT time of paracetamol. I run...

03 March 2019 4,355 3 View

Does anyone help in paracetamol impurities method?

I am trying to develop method for paracetamol impurities in oral suspension,at the moment I am using 20mM phosphate buffer but everytime the same mobile phase and same solution give me different...

11 November 2018 6,762 0 View

Capacity Factor in HPLC chromatography?

can any one share their expertise in Capacity Factor, I developed the impurities method and the asymmetry is about 1.0 for all the impurities and now I have been asked it should be more than 2 the...

11 November 2018 8,123 0 View

Force degdradation for pharmacutical product in method developmenet?

can anyone suggest as I cam across different paper doing the acidic and basic and stress oxidation for 60minuties on top bench and some leave for 7 days. Can anyone please suggest why there is...

11 November 2018 4,224 0 View

Can any one please tell me which other statistics can be used for IC50?

Hi Can anyone explain ,which other software or statistics can be used for determination of IC50 other than using Excel.

05 May 2016 5,237 2 View

How can I increase the expression of desired receptors?

Does anyone have any idea if estrogen (hormone) is fed to cell for certain amount of weeks and will it increase the expression of estrogen receptors (ER)? And can anyone send me paper for similar...

03 March 2015 3,301 2 View

Does any one know which cell line expresses 5-reductase enzyme?

Does any know whuch prostate cancer cell line express 5a-reductase enzymes

12 December 2014 7,509 3 View

Formic acid or tritiated water?

I was wondering that Aromatase assay is called tritiated water release assay and number of theories been proposed for release of formic acid and tritiated water release. does any knows that what...

12 December 2014 3,072 0 View

Can any one help with TLC mobile phase of androstanedione?

Since, I do not have standard steroid (Androstanedione), I was wondering that if any one can tell me what is the TLC mobile phase for androstanedione and is it UV-active or not. I want to check...

12 December 2014 549 3 View

Can anyone can give me a clue, which cell line expresses the 17B HSD3 prominently?

Hi I wondering if anyone can give me a clue, which cell line expresses the 17B HSD3 prominently. Please.

11 November 2014 1,893 2 View

Can anyone knows why highly fat content food is risk of cancer, what rational is involved?

Fatty food

11 November 2014 3,743 0 View

Which cell line expresses 17a-hydroxylase, 17,20-lyase enzymes, except NCIH295R cell line?

Can anyone help me?

06 June 2014 420 1 View

Which cell line except NCIH295R expresses 17a-hydroxylase 17,20-lyase enzymes?

05 May 2014 1,134 0 View

Can anyone help with a 17,20-lyase recombinant enzyme?

I have been trying to find a paper, wherein they use 17,20-lyase recombinant protein. Can I get help for paper or name of any company who has this protein?

04 April 2014 3,945 0 View

How do you detect dehydrotestosterone (DHT) on a TLC plate besides using iodine vapours?

see above

03 March 2014 1,693 2 View