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Questions related from Prabhuraj R S
I prepared PLGA nanoparticles. Then I loaded anticancer drugs in PLGA nanoparticles. Then I attached targeting ligands like folic acid (FA) and hyaluronic acid (HA) separately to target the cancer...
02 February 2020 318 11 View
I am working on nanoparticles for the treatment of cancer. We are planning to do antitumor efficacy in mice. People generally use intravenous route to inject nanoparticles to mice. I would like to...
04 April 2019 5,005 4 View
I am doing cell cycle analysis using Propidium iodide dye in flow cytometry. My samples are 1) cells 2)cells+ silica 3) cells+ drug 4) Cells+ silica-drug The cells treated for 24 hrs with the...
12 December 2017 1,430 4 View
I synthesised the mesoporous silica nanoparticles. Then I attached graphene nanoparticles with mesoporous silica nanoparticles. TEM images clearly show the attachment of graphene over mesoporous...
11 November 2017 4,286 22 View
I am working on mesoporous silica nanoparticles. One can find the loading and entrapment efficiency using UV method. For example, I did the TGA for mesoporous silica from 30-900 degree celsius and...
07 July 2016 9,639 9 View
The graph show cyctoxicity of different combination of chemo drugs on a cancer cell line. The graph compare the percentage of cancer cell growth inhibition and percentage of cancer cell killing...
07 July 2016 6,341 3 View
I am working on nanoparticles for the treatment of cancer. I am working with hydrophobic and hydrophilic drug. usually people (in papers) use 24 hrs for loading of drug in nanoparticle. My...
01 January 1970 8,007 8 View
If we change the PH of the solution from 7.4 to 9, it will affect the drug loading percentage in nanoparticles.
01 January 1970 4,541 4 View
I am working on mesoporous silica nanoparticles for the treatment of pancreatic cancer. I am planning to put PEG over the surface of the mesoporous silica nanoparticles. I want good suggestions...
01 January 1970 10,102 3 View
I am loading Gemcitabine HCl into mesoporous silica nanopariticles. I took 25 mg of mesoporous silica nanoparticles and 10 mg of drug for loading purpose. I used PBS 7.4 as a medium to load the...
01 January 1970 6,641 8 View
I am working with mesoporous silica nanoparticle for the treatment of cancer. I am interested to know how much amount of mesoporous silica nanoparticles internalized in cancer cells. I seed 1...
01 January 1970 5,018 5 View