Bably Khatun

10 Questions 20 Answers 0 Followers

Questions related from Bably Khatun

Is there any reference showing gradual dispersion of a drug (especially curcumin derivative) in cell culture media with time?

MTT assay demonstrated that there is no effect of a curcumin derivative at 24 h but shows good effectivity at 48 h. I think this might be due to the slow dispersion of the drug in the cell culture...

10 October 2019 9,906 2 View

How to calculate cumulative drug release ?

I have attached the method as well as calculations for drug release but could not find appropriate results even after several repetitions. It was clearly visible that there must be a high...

10 October 2019 8,826 3 View

Is there any reference showing proliferation of human lymphocyte cells (PBMCs) with increasing dose of any curcumin derivative?

while doing MTT assay in human PBMCs with doses increasing from 25microgm/mL to 100 micro gm/mL, I have found an increasing trend in cell viability. I could not find any reference or the reason...

10 October 2019 1,791 2 View

Can anyone say why hydroxypropylbeta cyclodextrin swells more in basic pH than i n acidic?

I have studied the swelling behaviour and drug release pattern from hydroxypropyl beta cyclodextrin where I have found that the swelling and release % was more in basic compared to acidic. It...

07 July 2019 7,926 2 View

Can HPLC be used instead of column chromatography for the purification and isolation of an organic drug molecule?

I have synthesized a drug molecule and now I need to purify and isolate it. Its difficult for me to do column chromatography. So I wanted to know if doing HPLC will serve the purpose or not. Thank...

06 June 2019 6,610 18 View

Can anyone help me analyse the XRD pattern attached?

I have tried to change the structure from CUR to CP. I know XRD is not mandatory here but since I did I would like to analyze the result. A very simple explanation will also be highly appreciated....

04 April 2019 2,594 8 View

Does the MTT assay of a sample show different result if repeated for several times?

If yes how can we compare the effectivity of a newly synthesized sample with the previous ones?

04 April 2017 1,565 0 View

Can anyone recommend a polymeric nanoparticle synthesis procedure to load a partially hydrophiic drug to get high loading effeceincy?

Can you please recommend me a polymeric nanoparticle system to load a partially hydrophilic drug for controlled release or tune the release behaviour

01 January 1970 2,902 4 View

Does sonication leads to breakdown of polymer nano/microparticles?

While preparing a drug loaded polyelectrolyte complex nano/micro particles using two oppositely charged polymers, the particle starts forming after the addition of second polymer (precipitation...

01 January 1970 9,341 10 View

Which one among these is better to write a manuscript: MS Word, Google doc or Latex?

The manuscripts in my field (polymeric Drug delivery) includes mostly images, a few tables and 2-4 equations. Also formatting the manuscript into different journal type and managing references is...

01 January 1970 8,003 7 View