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Questions related from Ali Gholamrezaei
Atropine is an antagonist of the muscarinic acetylcholine receptors located in end organs (e.g. heart) as well as in brain. While acetylcholine is released from the vagal efferent fibers,...
02 November 2019 2,742 1 View
I am using SAS for mixed model analysis, PROC MIXED with repeated measures. Does anyone have a code for calculating effects size, especially the partial-eta2? How accurate is to calculate...
26 February 2019 7,460 3 View
Visceral pain can provoke autonomic responses usually including tachycardia and pressor effects indicating sympathetic arousal. There are some evidence that visceral pain may provoke both...
11 September 2018 9,121 4 View
Slow breathing increases fluctuation of blood pressure over the breathing cycle which is followed by the larger amplitude of respiratory-sinus arrhythmia. One main mechanism is the baroreflex. In...
06 June 2018 6,705 15 View
There are some formula for estimating nares to lower esophageal sphincter distance in infants based on height. I'm looking for some data in adults to estimate such distance based on gender and...
11 January 2018 4,759 4 View
In an experimental study we tested various breathing exercises and monitored respiratory flow, beat-to-beat blood pressure, and heart rate. We developed MATLAB script for baroreflex analysis based...
01 December 2017 9,389 16 View
Hi, I'm looking for a relatively rapid viscero-somatic or viscero-visceral reflex responsive to esophageal pain that can be objectively measured?
30 May 2017 1,543 5 View
In one of our studies on the effect of various breathing exercises on Vagal activity and Baroreflex Sensitivity, subjects performed uncontrolled breathing, paced breathing at 0.23 Hz, and paced...
03 March 2017 9,500 3 View
Hi, In a study on the effects of breathing frequency manipulation on blood pressure variability we are going to perform spectral analysis of blood pressure. Each breathing block is 3 minutes long,...
19 February 2017 629 8 View
In an experimental study with healthy volunteers, we are going to test the effect of breathing pattern manipulation on esophageal pain. Esophageal pain will be induced by electrical stimulation....
09 February 2017 2,663 5 View
We are going to measure baroreflex sensitivity based on sequence and spectral method. For the sequence method we need the number of up/down sequences, and also we need to play with the criteria of...
07 December 2016 9,782 16 View
To study visceral pain modulation we are working on appropriate models of esophageal pain to be used in experimental studies with healthy volunteers and then in patients. For mechanical...
01 December 2016 9,862 1 View
We use the analogue output of the Portapres device for monitoring continuous blood pressure. Is band-pass filtering necessary for such blood pressure wave analysis? What should be the low/high...
04 November 2016 3,002 14 View
In respiratory research a breathing apparatus consisting of mouthpiece, filter, Pneumotachometer, and non-rebreathing valves plus some connectors are usually used. Although a non-rebreathing valve...
20 October 2016 9,276 7 View
Balloon distension at distal esophagus is a method of visceral pain induction. We are looking for reliable methods for making balloons. The balloon will be fixed at the end of a NG tube and be...
21 June 2016 2,046 7 View
Investigators use cardiac cycle (systole vs diastole) to evaluate effects of interoceptive afferent signaling on cognitive and emotional processing. Some believe that baroreceptor activity is...
28 May 2016 5,031 4 View
Slow breathing, usually at frequency of 0.1 Hz, is a method of relaxation and supposed to increase parasympathetic activity. Heart rate variability is used as a marker for autonomic response to...
28 December 2015 7,646 34 View
It is still controversial whether paced breathing is necessary during measurement of heart rate variability and spontaneous baroreflex sensitivity. The other question is that if paced breathing is...
30 October 2015 6,862 11 View
One method for evaluating esophageal pain sensitivity is by balloon distension, at the distal esophagus. The intra-thoracic pressure is changing over the breathing cycle, being more negative...
29 September 2015 370 2 View
Slow breathing at 6 breaths per minute increases heart rate variability and baroreflex sensitivity [PMID: 24092689, 19608928, 16752104]. Does the body posture (supine vs. sitting) matter in this...
02 September 2015 210 3 View
Studies have shown that slow and deep breathing (SDB) increases baroreceptor sensitivity (BRS), but the mechanisms are not clear. Is it due to the increased blood pressure oscillation during SDB?...
05 August 2015 1,454 6 View
Extracorporeal shock wave lithotripsy accompanies with pain. Is it worthwhile to perform intercostal nerve block for pain relief during ESWL?
02 March 2015 8,643 6 View
Baroreceptors in the carotid sinus are stretch receptors in the arterial wall. How these receptors are stimulated by external pressure as with carotid massage?
22 November 2014 3,298 12 View
In a study of extra-intestinal symptoms in IBS patients we found that thigh pain, muscle and joint pain, and back pain are more frequent in IBS-C than IBS-D and IBS-M. What could be the underlying...
06 October 2014 9,202 5 View
Two studies up to now have shown an association between adenosine deaminase activity and disease activity in patients with Crohn’s disease and ulcerative colitis. We conducted a similar study in...
31 July 2014 2,607 2 View
In an observational study on the frequency of restless legs syndrome (RLS) and its contributing factors among patients with systemic lupus erythematosus we found a protective role of using...
19 May 2014 6,457 11 View
Vitamin D deficiency is common in patients with inflammatory bowel disease. Some studies in non-IBD patients are in favor of oral therapy versus injection therapy of vitamin D deficiency....
11 January 2014 4,595 26 View
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07 January 2014 2,549 2 View
We recently conducted a trial on the efficacy of alprazolam as premedication for upper GI endoscopy. We found that presence of hiatal hernia is an independent predictor of pain/discomfort during...
19 October 2013 2,781 16 View
Which of the following or any other questionnaires do you think is best to measure coping mechanisms in an outpatient medical setting and why? - Jalowiec Coping Scale - The COPE inventory - Ways...
22 August 2013 2,893 20 View
Clopidogrel plus aspirin are standard dual antiplatelet therapy after PCI for preventing cardiovascular events and stent thrombosis. Large studies have been conducted to investigate if double-dose...
28 February 2013 7,090 8 View
