One method for evaluating esophageal pain sensitivity is by balloon distension, at the distal esophagus. The intra-thoracic pressure is changing over the breathing cycle, being more negative during inspiration and less negative during expiration. Should esophageal pain sensitivity test by balloon distension method be adjusted according to the change in intra-thoracic pressure during respiratory phase?
yes of course .
if you have enough sample size with testing in different phase of breathing , you will be able to form two categories, then it is possible to compare the results between categories
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Dear Dr. Farajzadegan,
Yes, but the problem is that in our laboratory study we can not include a large sample of subject and we already have several other conditions and interventions to compare.
One possible solution is to fix the timing of balloon distension to the respiration phase; e.g. at end inspiration or at early expiration.
Interestingly, I found almost no description and solution for this concern in the literature on esophageal pain sensitivity testing by balloon distension !
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