Ahmad Zidan

35 Questions 21 Answers 0 Followers

Questions related from Ahmad Zidan

How to retrieve the associated diseases for a list of reference SNPs?

I have a list of reference SNPs IDs (rsid) and I need to retrieve the associated diseases ... what are the suitable bioinformatics tools or databases?

02 February 2020 4,942 1 View

How to get a Phased VCF file?

Can I phase VCF file after it has been generated ? Or I must have a phased BAM to get a phased VCF? Which tool is best used for this purpose?

10 October 2018 773 0 View

Gene list - disease association ?

I have a gene list and want to map it to human diseases to know what are the most probable disease relates to my list. What is the best bioinformatics tool to do this job?

06 June 2018 3,681 1 View

Is there a complete list of files used in the field of "omics" ?

I find different types of files in field of bioinformatics ... where can I find a complete list and description for these files?

03 March 2018 1,222 0 View

23 &Me variant names and genotypes ?

In 23&Me files for personal genetics services, I found some genetic variants named like (i6033918) and the genotype is (II). What does this mean?

10 October 2017 5,737 3 View

Where to find a database linking genetics and facial topology?

01 January 2017 9,786 1 View

Where to find a list of activators and inhibitors of an enzyme ?

I need a downloadable list of structures of activators and inhibitors of a certain enzyme ... where can I find a database containing this data ?

09 September 2016 426 4 View

How to detect the best variant affecting patient's response to a drug?

I detected a set of patients that have a high response to a drug. Each patient has 40 different reads ( 20 nominal and 20 continuous) resemble certain genetic and expression variations. How should...

04 April 2016 523 3 View

Some bioinformatics tools need Linux platform, others need Windows. What can I do for this?

Does anyone have an experience in getting Windows and Linux on the same computer (Laptop)?

11 November 2014 8,809 5 View

Is there a source where I can find the 3D structures of the different protein alleles?

I need 3d structures of different alleles of the same protein.

11 November 2014 1,218 3 View

How can I download the catalytic unit of an enzyme?

I need to download only the catalytic unit not all the enzyme seq.

06 June 2014 7,966 2 View

Is there an in silico method to predict the action of a ligand on an enzyme?

Can I computationally predict whether my ligand is an activator or inhibitor to the enzyme?

05 May 2014 9,108 12 View

Is there a difference between the binding mode of enzyme activators and inhibitors?

Assuming that the two types of ligands bind to the same binding pocket.

05 May 2014 4,100 1 View

Where can I find a PDB file for chemicals (e.g drugs)?

Some tools need PDB codes for drugs, not MOL nor SMILES.

05 May 2014 5,906 7 View

Can any one explain briefly different types of electromagnetic waves? Is light an EM wave?

I'm a little bit confused about the different types of EM waves.

04 April 2014 8,319 4 View

Does it make sense that 98% of the genome is "non coding"?

According to the central dogma, only 2% of the human genome is coding for proteins.

04 April 2014 6,893 9 View

Is it really "JUNK" DNA ?

Http://www.genengnews.com/gen-news-highlights/junk-dna-tied-to-heart-failure/81249794/

04 April 2014 5,086 2 View

Is there software to predict Kd or Ki for ligand-protein complex ?

I need to computationally predict Kd constant for a drug-enzyme.

04 April 2014 1,603 1 View

I need to examine a substrate-enzyme relationship between a drug and an enzyme. What constant is better to use?

Should I use IC50 or Kd, or something else?

04 April 2014 2,513 8 View

What is the meaning of x- coverage in next generation sequencing? Is it different from % coverage?

A little bit confused about x- coverage and % coverage

04 April 2014 9,846 13 View

What is meant by the odd ratio (OR) in pharmacogenomics?

What is meant by an odd ratio > 0.3 in a study?

04 April 2014 3,062 8 View

What is the size of data in gigabytes that is produced from a whole genome sequencing?

I need to know the size in gigabyte not in giga base-pairs.

04 April 2014 8,858 7 View

How often do de novo mutations occur in the human genome?

If the same human genome is sequenced after five years of its first sequencing, will it be different?

04 April 2014 3,239 7 View

Does the 3.3 GB of the human genome belong to one set of chromosomes (23 chromosome) or to the all diploid set (46 chromosome)?

I've read on a website that whole genome sequencing is done only to one set of chromosomes (23 chromosome). Is this true?

04 April 2014 3,705 5 View

What is a reference genome?

When we detect genetic variant we compare the sequenced genome to a reference genome. The question is about Human Genomes.

04 April 2014 6,497 6 View

What is 'big data' and how it can be used in healthcare?

Next generation sequencers (NGS) produce big data outputs. Are there specialized databases for this big data?

03 March 2014 957 2 View

What is systems bioinformatics?

01 January 2014 1,288 0 View

Where can I publish a short note in the field of insilico research?

I need to publish an interesting finding as a short communication till I finish my work. I need a journal that publishes insilico work without asking me to validate work by in vivo or in vitro...

11 November 2013 9,737 1 View

Is any one interested in detection of the mode of action of Nitazoxanide as an anti-HCV drug?

I have good in silico results that need to be verified with in vivo and/or in vitro experiments. If anybody is interested, please get in touch.

11 November 2013 3,373 0 View

Is there a site for different types of computational biology tools and databases?

I need one site for all omics resources, what is the best site?

10 October 2013 1,914 3 View

Is there a database for drug related gene expression information?

Database for microarray data after administration of a certain drug.

10 October 2013 7,807 1 View

What is the significance margin of Tanimoto coefficient to compare the chemical similarity?

I have got a score of (0.65) when comparing two drugs with a tool comparing the chemical similarity using Tanimoto coefficient. Is this score significant or not?

09 September 2013 1,444 2 View

What is the best in silico tool for scoring chemical similarity?

Scoring ligand similarities.

09 September 2013 4,564 0 View

Can someone advise on how to read Swiss docking results?

How to expect the affinity of ligand-target from the swiss docking results?

08 August 2013 5,060 0 View

What is the best review source for the applications of Bioinformatics in Pharmacy?

I need a recent review that link the Bioinformatics to pharmaceutical science.

08 August 2013 2,317 7 View