I have good in silico results that need to be verified with in vivo and/or in vitro experiments. If anybody is interested, please get in touch.
I have a list of reference SNPs IDs (rsid) and I need to retrieve the associated diseases ... what are the suitable bioinformatics tools or databases?
01 February 2020 4,835 1 View
Can I phase VCF file after it has been generated ? Or I must have a phased BAM to get a phased VCF? Which tool is best used for this purpose?
09 October 2018 668 0 View
I have a gene list and want to map it to human diseases to know what are the most probable disease relates to my list. What is the best bioinformatics tool to do this job?
05 June 2018 3,581 1 View
I find different types of files in field of bioinformatics ... where can I find a complete list and description for these files?
02 March 2018 1,119 0 View
In 23&Me files for personal genetics services, I found some genetic variants named like (i6033918) and the genotype is (II). What does this mean?
09 October 2017 5,625 3 View
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31 December 2016 9,682 1 View
I need a downloadable list of structures of activators and inhibitors of a certain enzyme ... where can I find a database containing this data ?
08 September 2016 325 4 View
I detected a set of patients that have a high response to a drug. Each patient has 40 different reads ( 20 nominal and 20 continuous) resemble certain genetic and expression variations. How should...
03 April 2016 422 3 View
Does anyone have an experience in getting Windows and Linux on the same computer (Laptop)?
10 November 2014 8,696 5 View
I need 3d structures of different alleles of the same protein.
10 November 2014 1,115 3 View
How to calculate the RMSD values for a MD simulation using MOE?
07 August 2021 0 0 View
When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.
16 June 2021 0 0 View
Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...
03 March 2021 5,978 5 View
Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...
02 March 2021 4,569 4 View
We have synthesized various metal complexes with different environment around the metals. Now to see the application of synthesized complexes we need this study also. we are also interested in...
01 March 2021 1,899 2 View
I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...
01 March 2021 8,544 1 View