Hi, dear dr

Sure, Alcohol is a rapidly evaporating volatile substance, during which the skin loses part of the water and its temperature, and that loss affects the skin's moisture and threatens to dry out. As a result, cracks occur in the skin and because of it the skin can penetrate any infection causing it to be exposed to infections. As well as increased sensitivity to the skin and affects the natural flora of the skin and increases the resistance of bacteria to antibiotics

Hi,

Commercial alcohol based sanitizers are generally a compound of the alcohol (like ethanol, isopropyl alcohol) and one or more emollients to mitigate the drying effects of the alcohol component.

This makes good for the damaging effect of alcohol to the skin.

Since "excessive use" has not been defined, use of these sanitizers within the guidelines of the manufacturer would be considered safe.

However, there may be other ingredients like stabilizers, scents, or one or more of the emollients themselves being potentially allergens.

Also, there are certain bacteria becoming slowly alcohol tolerant.

I don't know of any publications or findings about topic use alcohol "increasing the resistance of bacteria to antibiotics" though.

By the way, soaps may dry the skin as well. Therefore, these contain emollients as well generally.

So, there is no real silver bullet. It's a bit more complicated altogether.

Sure.

Usually no, unless one is allergic to it

Thanks all

See this reference: https://www.ncbi.nlm.nih.gov/books/NBK144008/

Contact dermatitis is a problem

Yes, there could be irritant contact dermatitis if the alcohol

content is too much.

It can also cause excessive xerosis.

Por el efecto captador de agua produce una sequedad de la piel que si ya está afecta de algún problema de eccema u otra patología de la piel, la empeoraría.

The main concerns about the effects of alcohol (skin dryness and the resultant effects) on the skin as found in alcohol based sanitizers are made very mild by the presence of the humectants such as glycerine(glycerol). However, the main concern would be allergy or intollerant skin reaction to the fragrances in the sanitizers . So as you follow manufacturers guide on frequency of use, watch out for ingredients present and any intorant skin reaction (usually due to the fragrances)which is person-specific and usually not captured in the guidelines. Raihana Kanth

Glycerin is a humectant indeed, and extremely hygroscopic, meaning it readily absorbs water from other sources. So, in part, glycerin works because of its ability to attract water from the environment and from the lower layers of skin (dermis) increasing the amount of water in the surface layers of skin.

Another aspect of glycerin's benefit is that it is a substance found naturally in skin.

In that respect it is one of the many substances in skin that help maintain the outer barrier and prevent dryness or scaling anyway.

However, high levels of glycerin has no proven increased benefit for skin. In fact, pure glycerin (100. concentration) on skin is not helpful and can actually be drying, causing blisters if left on too long as they can increase water loss by attracting water from the lower layers of skin (denmis) into the surface layers of skin (epidermis) where the water can easily be lost into the environment.

So, the concentration is to be watched.

Emollients are the better way.

Dryness

irritant

breakdown of skin

resistant to protection in long run

True, humectants(such as glycerin) work in line with their being hygroscopic but the moisture absorbed is preferably from the surrounding atmosphere than from the layers underneath the epidermal skin surface. To put in context , at the concentration humectants are employed in sanitisers(usually 0.25-1.0%) they are known to be safe to keep the skin hydrated.

Thank you for your update.

Yes there can be a negative effect especially cumulative irritant contact dermatitis due to tetrahydroxypropyl ethylenediamine component in the sanitiser.

thank you