Magnetic nanoparticles of size 5 nm
Frequency applied= 247 kHz
Magnetic field magnitude applied= 31.5 kA/m
Temperature of sample detected with an Opsens IR-sensor OTG-A-62 or with an IR pyrometer
I assume you are using iron oxide nanoparticles. In that case, the particles are too small to show any appreciable heating at room temperature. (see Fig 5 in Rosensweig, Journal of Magnetism and Magnetic Materials 2002) Moreover, if you are measuring the particles in an aqueous suspension, the heat capacity of water is very high, so the heat that has to be released by the particles to achieve a measurable temperature increase is also high. Also increasing the concentration of particles in your sample could help you to detect an appreciable temperature increase.
I hope you found this useful,
Irene
Dear all,
if I understood well the question, you are using an external stimuli to release drug loaded into a polymeric nanoparticles. First do you have really a polymeric vehicle that shows a response to an applied magnetic field. Please it would be great if you add and additional details. Regards
generally drugs get releases from the polymeric carriers if it it changes carrier phase(transition) at some particular temperature(in this case).. What is the transition temperature of your polymer? I may be that increment in the temperature is too small to cause a phase change in polymeric network.
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