I am working on effects of some natural products on ATPases, some inhibited the enzymes while other activated. The confusion is that I expect, for example to have the same type of inhibition (say competitive) for a particular inhibitor of a particular ATPase in all the three blood types. i.e if product A has competitive inhibition on enzyme EZ in HbAA, it should have the same competitive inhibition on the same enzyme in either HbAS or HbSS too. I want to know if it is possible to have different type of inhibition of the same inhibitor on the same enzyme in different blood types.
Thanks