In both CMS and post-synaptic myasthenia gravis, I understand that the receptors of acetylcholine are impaired. Why then would an acetylcholinesterase inhibitor treats one problem and aggravates the other ?
https://www.researchgate.net/profile/PF_Zabrodskii/research
Antibiotic resistance is a pressing global and local health concern. Outpatient settings play a crucial role in antibiotic consumption and the emergence of resistant bacteria due to the frequent...
09 April 2024 6,004 0 View
Hi, I am interested to study myelinosome. I know it can be seen well in electro microscopy, however I was wondering if I could stain them with an antibody ? Thank
10 March 2024 8,329 0 View
This inquiry is related to a 2019 journal article authored by Nick Neuwinger et al., which explores the effect of underfilling vacuum blood collection tubes on the elevation of lactate...
05 February 2024 3,059 1 View
Can you provide articles on behaviors that inhibit team development in healthcare/ Thank you Pauline
05 February 2024 8,421 3 View
I want to do an adaptive N-back task of 20 stimuli, it has 14 non-targets (70%) and 6 targets (30%), in order for them to end up with an N-back level that is doable for them but can still improve...
29 November 2023 2,237 3 View
I am a 3rd year student, and as per the University's requirement; every year 3 student is required to write a proposal. However, before a proposal is written, a literature review is done first.
20 August 2023 4,487 2 View
I need data visualization to illustrate the prevalence of traditional style in the operation of family businesses.
15 August 2023 7,169 0 View
I want to see if there is a significant difference in BHB concentration between 5 age categories in some farm animals. Farm should be a random effect in the model. The issue is that BHB...
21 June 2023 5,234 0 View
What is the sample size calculation for a discrete outcome (count variable)? For example, I want to design a trial with a placebo and a treatment. Alpha is 0.05 and power 0.8. The outcome is the...
27 March 2023 8,189 11 View
How to calculate the appropriate sample size for the development of a new clinical test? The test would either be a quantitative test if the accuracy is good enough (i.e., test would predict a...
29 January 2023 1,594 4 View
Is there any benefit in knocking out the interferon receptor in 293T cells? In the context of creating RNA viruses 📷
13 July 2024 3,382 0 View
I performed fea on tensile dog bone specimen using ANSYS static structural and also tried using ANSYS explicit dynamics. In experimental result the load is 500 N and deformation is 0.6 mm...
13 July 2024 3,631 4 View
Hi, I'm working on heart flow cytometry, and I use anti-mouse CCR2-BV785 (biolegend, cat150621) for staining, 20 minutes, 4 degree. But I couldn't see any CCR2+ cells. So I'm not sure if it's...
03 July 2024 3,969 4 View
With a stressful lifestyle, we start experiencing forgetfulness at an early age, which can accelerate the onset of Alzheimer's disease symptoms in young people as early as their 30 years old....
24 June 2024 938 1 View
Dear All, I am writing to solicit your expertise regarding the application of Higher-Order Shear Deformation Theory (HSDT) and First-Order Shear Deformation Theory (FSDT) for structural...
22 June 2024 7,751 5 View
I conducted a tensile test to analyze the strength of a welded joint and to implement an FEM model. Due to the high hardness of the base material, slippage between the grip and the base material...
10 June 2024 5,736 6 View
Hi, I'm working on the immune cells in the heart and have a problem with CCR2 marker. I did some research and found there's CCR2+ monocytes in heart failure mouse model. When I analysed CCR2...
08 June 2024 7,315 5 View
Good day, I am trying to model the GABA A receptor, with different subunits. I selected the templates with the highest percent of identity, but as a result of the modeling I got a protein with...
02 June 2024 5,489 2 View
I have purchased Acetylcholiesterase from Electrophus electricus (electric eel), C3389-2KU, following details are written on the enzyme vial. Type-VI S lyophilized powder 200-1000 Units/mg...
31 May 2024 6,444 1 View
I have a problem, in additive manufacturing (here specifically LPBF), if you make parts with different shapes through a fixed printing process, the parts will deform due to different geometry...
20 May 2024 7,549 3 View