Why does atoxigenic Aspergillus flavus AF36 not make aflatoxin?

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John S. Bennett

This is due to a SNP in the pksA gene. See these articles for more information. Article An isolate of Aspergillus flavus used to reduce aflatoxin co...

https://academic.oup.com/femsle/article/268/2/231/657121

Stephen M Marek

Thank you, John!

Safieddin Inbaia

The variation between isolates is likely to have arisen from genetic differences between them, which may contribute to mycotoxin production. Because some isolates may lack the gene require’s for mycotoxin production. However, a species or a strain may posses the gene and appropriate enzymes needed for the production of particular mycotoxins, but for some reason , the toxins are not formed in any substantial amount under lab and field condition.

Shaoqin Zhou

Aflatoxin producers are extremely sensitive to incubation conditions. Such as the substrates, incubation temperatures, CO2 concentration, and so on.