Why do the silica nanocapsules release the highest value of MBT at neutral pH?

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Mahta shariat razavi

Thanks for your attention

pKa is about 7 at 20°c

Water solubility: 117mg/L ,Although in some cases it has been reported in the range of 100 to 1000 mg/L

Omar Gonzalez-Ortega

You can find information to help explain your results here:

Article A computational UV–Vis spectroscopic study of the chemical s...

How did you keep silica from dissolving at high pH?

Thanks for your help

Due to what this article said, pKa is almost equal to Neutral pH. Besides, MBT- was released at pH>7 and MBTH+ was released at pH

According to the manuscript:

"On the other hand, functionalized mesoporous silicas were not stable in alkali solutions due to the breaking of the Si–O–Si bonds by hydroxide ions attack", hence my question.