Cerium dioxide (CeO2), also known as ceria, is a nanomaterial that has shown potential for use in cancer treatment due to its unique properties. Here are some of the reasons why CeO2 is being investigated for use in cancer treatment:
Antioxidant properties: CeO2 nanoparticles have been found to possess potent antioxidant properties, which can help protect cells from damage caused by reactive oxygen species (ROS). ROS can cause DNA damage, which can lead to cancer.
Anti-inflammatory properties: CeO2 nanoparticles have also been found to possess anti-inflammatory properties. Chronic inflammation is associated with cancer development, and reducing inflammation can help prevent cancer.
Biocompatibility: CeO2 nanoparticles are biocompatible, which means they are not toxic to cells and can be used safely in the body. This makes them a promising material for use in cancer treatment.
Drug delivery: CeO2 nanoparticles can be used as carriers for drugs, allowing for targeted delivery to cancer cells. This can increase the effectiveness of cancer treatment while reducing the side effects of chemotherapy.
Imaging: CeO2 nanoparticles can also be used for imaging cancer cells. This can help doctors detect and monitor cancer, allowing for more effective treatment.
Overall, CeO2 nanoparticles show promise for use in cancer treatment due to their unique properties, including antioxidant and anti-inflammatory properties, biocompatibility, drug delivery, and imaging capabilities. However, more research is needed to fully understand their potential and to develop safe and effective treatments.
Many thanks for your interesting question! To the best of my knowledge, CeO2 nanoparticles were discussed as an additive for diesel fuel to reduce the particle concentration in diesel engine exhaust gas. Moreover, Ce4+ is used as a strong oxidiser in analytical chemistry for redox titrations. Finally, many scientific works deal with the cytotoxicity of CeO2 nanoscale particles, e.g.
- Toxicity of CeO2 nanoparticles - the effect of nanoparticle properties
- Redox chemistry of CeO2 nanoparticles in aquatic systems containing Cr(vi)(aq) and Fe2+ ions
- Schwotzer, Daniela (2018): Investigations on the Toxicity of CeO2 Nanoparticles after Subchronic Inhalation of Low Doses. Hannover. Online unter: https://elib.tiho-hannover.de/receive/etd_mods_00000037
You can find some info about nanoparticles used in cancer therapy, e.g. Au, Fe-oxides, HfO2, 177LuPO4, in one of our recent presentations at RG: UV-Emitting Nanoscale Scintillators for Cancer Treatment, April 2022, Infineon University Day
Nano particles(CeO2) are used in cancer treatment because it can absorb and create heat. This heat can be directed to the tumor to destroy the cancer cells while minimizing damage to healthy cells.That's why.
Please read its CeO2 matrix to get an idea.
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