What is the best device to identify gold and estimate the volume of a primary gold ore?

In the market, there are many devices that offer varying features to hunt natural gold. I am very suspicious if these devices really delivery what they say. The prices vary considerably and some...

16 November 2020 2,998 4 View

How to overlay and align different scale raster?

I need to overlay two rasters and the pixels of they must be in the same position to each other. I need this to perform a ecological niche model using a package in R. For this end all images must...

20 August 2020 9,503 4 View

How to infer Causality in a observational data?

My Machine Learning model show in different ways, high correlation between parents' education and student's outcomes. I 'm trying to identify a causal relationship in a separate model since the...

11 June 2020 4,186 7 View

Can anyone give suggestion were i can find a platform on ANOVA variance analysis? any website or Research articles?

Dear can anyone give suggestion were i can find a platform on ANOVA variance analysis? any website or Research articles? (analysis of variance, a statistical method in which the variation in a...

31 January 2019 4,004 6 View

Can trypsin affect the cellular receptor to dengue virus infection?

The trypsin can change the VERO receptors used by dengue virus infection.

17 August 2016 1,879 3 View

How can I isolate Canine Dispar Virus (CDV) of dog plasm?

02 August 2016 2,327 3 View

How I can lyse virions?

I need a viral lysate. There are some substance to it? Something that disrupts the lipid envelope.

20 July 2016 4,734 1 View

Can filter dengue virus in 0.22 micron?

I need remove cell debris, however i don't know if can filter the dengue virus in 0.22 um filters.

20 July 2016 2,113 2 View

Hi I want to know if is possible to see any preferential crystalline orientation in freestand nanotubes only by x-ray diffraction study? If yes, why?

xray difraction

08 January 2016 8,961 13 View

How can I remove bacterial contamination from fixed human cells?

17 December 2014 7,626 2 View

Which of the Covid-19 Vaccines would elicit the best immunoprotection and why?

I want to know which of the available Covid-19 Vaccines would elicit the best immunological response and why

02 March 2021 1,388 3 View

Experimental Design: How deal with pseudreplicates with immunological and clinical-chemical paramaeters?

Hello everybody, I am investigating the influence of a toxinon various clinical-chemical and haematological parameters in fish. I have three treatments (control, low dose, high dose) in my...

24 February 2021 1,243 1 View

Looking for advices and tips to improve the staining and the gating strategy in human blood?

Hi, I am staining a human blood with CD19, CD3,CD14 and CD16. My gating strategy in FlowJo goes like this: - First, I gate a general population SSC-A VS FSC-A => Then gate for single cells, =>...

21 February 2021 5,724 4 View

Can you polarize Jurkat cells into different T helper subsets?

I am wondering if anyone has had success with in vitro polarization (via cytokines) of Jurkat cells. My goal is to understand the affect of a drug on Treg induction and differentiation. I...

12 January 2021 3,606 2 View

Can only the spike protein of the virus provide immunity?

Virology, microbiology, immunology, vaccine

21 December 2020 424 16 View

Can somebody recommend me a decent textbook to learn more about signaling pathways and their mechanistic principles in general?

I studied biochemistry and molecular biology in my bachelors and Immunology in my masters. I never came across a suitable course for general signaling pathways and principles. My interest is...

13 December 2020 5,690 5 View

Is it possible to extract DNA or RNA from paraffinized biopsies ?

My lab have some skin biopsies that were previously conserved in paraffine , and i wanted to know if it is possible to extract DNA or RNA from them.

06 December 2020 7,964 6 View

Could the desmin mutation in myofibrillar myopathy be caused by an infection?

A patient with desminopathy (mutation Thr341Pro DES in a heterozygous state) with the progression of the disease has a decrease in taste and smell, immunosuppression, and an increase in IgA in the...

02 November 2020 5,886 6 View

Whis HLA-A2 TAAs are best for DC pulsation and CD8+ cytotoxic T cell induction?

When looking to establish Ag-specific CD8 cytotoxic T cells with autologous dendritic cells, there are numerous tumor-associated Ags to choose from. Does anybody know which Ags give the best...

27 October 2020 2,068 2 View

Resuspending cell pellet after ficoll centrifugation?

In my current project I am planning to isolate mononuclear cells from peritoneal ascites of cancer patients using ficoll centrifugation. However, following isolation of the mononuclear cell layer,...

26 October 2020 5,966 4 View