In late AMD is possible to enhance vision in the PRL in order to reduce crowding and improve visual acuity using a training based on perceptual learning.

There has been some interesting work on high dose omega 3 fatty acids and AMD. This paper by Barry Sears of the Zone Diet fame is promising. One should only take pharmaceutical grade omega 3 like he sells on his web site.

http://www.sciencedirect.com/science/article/pii/S221343441300042X

Hi, 

The following works might be of some help !!!

1.             Chew EY, Clemons TE, Agrón E, et al. Long-term effects of vitamins C and E, β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35. Ophthalmology. 2013;120(8):1604-1611.

2.            Age-Related EDS. Lutein+ zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA: the journal of the American Medical Association. 2013;309(19):2005.

3.            Chew EY, Clemons TE, SanGiovanni JP, et al. Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3. JAMA ophthalmology. 2014;132(2):142-149.

4.            Ma L, Yan S-F, Huang Y-M, et al. Effect of lutein and zeaxanthin on macular pigment and visual function in patients with early age-related macular degeneration. Ophthalmology. 2012;119(11):2290-2297.

5.            Ma L, Dou H-L, Wu Y-Q, et al. Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis. British Journal of Nutrition. 2012;107(03):350-359.

6.            Evans JR, Lawrenson JG. Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration. The Cochrane Library. 2012.

7.            Meagher KA, Thurnham DI, Beatty S, et al. Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration. British Journal of Nutrition. 2013;110(02):289-300.

8.            Arnold C, Winter L, Fröhlich K, et al. Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: a randomized trial. JAMA ophthalmology. 2013;131(5):564-572.

9.            Tian Y, Kijlstra A, Webers CAB, Berendschot TTJM. Lutein and Factor D: Two intriguing players in the field of age-related macular degeneration. Archives of biochemistry and biophysics. 2015.

10.          Liu R, Wang T, Zhang B, et al. Lutein and Zeaxanthin Supplementation and Association With Visual Function in Age-Related Macular Degeneration. Investigative ophthalmology & visual science. 2015;56(1):252-258.

11.          Margrain TH, Boulton M, Marshall J, Sliney DH. Do blue light filters confer protection against age-related macular degeneration? Progress in retinal and eye research. 2004;23(5):523-531.

Thank you very much .