For all I know, the underlying adhesive chemistries (acrylic, silicone, polyuerethane, hydrocolloid, rubber, hydrogels, etc) play a crucial role for potential skin irritation.
Which skin adhesives and wet electrodes typically cause most severe skin reactions (allergies, itching, redness etc) during long-term wear (few days)? What is the influence of adhesive chemistries on skin reactions?