Hello Everyone,

I have already formulated and modified the surface with PTMS of mesoporous silica nanoparticles. And also loaded drug in it. But, I am facing a problem when suspending the blank and drug-loaded NPs to PBS for cellular studies. As our drug is very hydrophobic in nature suspending the NPs to PBS was a problematic issue. Which formulation, surface modification, and drug loading approach would be best for a hydrophobic drug for proper cellular studies?

Thank you.

Dipti Debnath