Is it just to make question?

How you can administrate oxytocin starting from very low dose and increasing it step by step for hours?

Dr. Ospan Ur question is not clearly understood.

OK, I misunderstand your question.

What do you mean PPH?

Oxytocin can be administered in usually used IV fluids by obstetricians i.e.0.9% saline, Ringer lactate or 5% dextrose. However, if high dosage of oxytocin is to be administered, it is better to avoid 5%dextrose because of possible water intoxication

Oxytocin has amino-acid homology similar to arginine vasopressin. Thus not surprisingly, it has similar antidiuretic action, and when infused at dosages of 20mIU/min or more, renal free water clearance decreases markedly. If aqueous fluid are infused in appropriate amounts along with oxytocin, water intoxication can lead to convulsions, coma, and even death. In general, if oxytocin is to be administered in high doses for a considerable period of time, its concentration should be increased rather than increasing the flow rate of more dilute solution. Consideration also should be given to use of either normal saline or lactated Ringer solution in these circumstances.

There are also a number of cases reported in the literature where high i.v. doses of oxytocin administered along with a large volume of electrolyte-free fluid have resulted in the development of water intoxication / hyponatremia.

Ref: William's Textbook obstetrics

Is this question about induction of labour or augmentation?

Both

There is no research supporting induction for postdates. There is very few reasons to induce labor according to research. Why are you inducing ?

No individual study with adequate sample size has been published, nor would a meta-analysis based on the current literature be sufficient. The optimal management of pregnancies at 41 weeks and beyond is thus unknown.

WENNERHOLM, U.-B., HAGBERG, H., BRORSSON, B. and BERGH, C. (2009), Induction of labor versus expectant management for post-date pregnancy: Is there sufficient evidence for a change in clinical practice?. Acta Obstetricia et Gynecologica Scandinavica, 88: 6–17. doi: 10.1080/00016340802555948

Thank you George for your reference citation. In augmentation/induction of labour, i prefer normal saline or ringers lactate, not 5%dextrose water, NEVER 10% Dextrose water to decrease the danger of water intoxication.

5% Glucosae

D5LR 1 liter plus 1 ampule of oxytocin, titration

Concur with Wilma de la Cruz

Ringer lactate only.

Saline or ringer solution are better than non electrolytic solutions to decrease fluid retention . Glucose solutions better reserved for nourishment with low intake in labour.

Ringer lactate or normal saline

Oxytocin is compatible with all type of I .v fluids like RL or NS (0.9%) or D5% solutions but Keep in mind that either of fluid may restricted or avoided like RL should be avoided in increased Lactic acid level or NS in case of Increased Na level