In the HPLC, we can use differents detector methods to quantify the cannabinoid content from the flowers of Cannabis sativa. Most populars detectors are:
1. UV
2. Diodo Array Detector
3. Mass spectrophotometer
Which one you condider better and why?
Due to the large variety of cannabinoids, the use of MS detector is better than Uv and DAD detractors for their determination because the spectra overlap in the UV and DVD detectors is higher than MS detector.
The presence of MS detector database can also help identify these compounds easily.
Please look at the following below links which may help you in your analysis:
https://www.sielc.com/cannabis-analysis
https://jast-journal.springeropen.com/track/pdf/10.1186/s40543-018-0159-8
https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/cannabis-testing.pdf
Thanks
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