I think you can extract using methanol or ethanol to get  most of the constituents directly (usually I did this, for metabolite profiling) , but you can also extract by using first hexane than extract the residue methylene chloride, than acetone and at last using methanol (I used this method if I have a great amount of plant materials and I want to isolate certain metabolite(s))

Dear Thabet

Similar queries were raised by several other RG members and by following the threads you will be greatly benefited. I am attaching a few for ready reference. You can view many more.

Good luck

https://www.researchgate.net/post/How_can_we_extract_and_isolate_steroids_form_dried_plant_tissue

https://www.researchgate.net/post/how_could_be_assayed_the_total_saponins_in_a_plant_extract

https://www.researchgate.net/post/How_to_isolate_an_active_compound_from_crude_plant_extract

https://www.researchgate.net/post/How_can_I_isolate_a_purified_compound_from_the_plants_extract

https://www.researchgate.net/post/Can_someone_suggest_me_an_efficient_method_to_extract_coumarin_from_plant_sources

https://www.researchgate.net/post/What_is_the_best_way_to_isolate_a_phyto_compounds_from_plant_extracts

https://www.researchgate.net/post/Can_a_solvent_effect_the_nature_of_plant_constituents_or_the_structure_of_a_natural_plant_product

https://www.researchgate.net/post/Can_someone_list_out_the_methods_of_extraction_crude_extract_compounds_isolation_purification_identification_and_structural_elucidation

I think Dichloromethane methanol mixture is the best

It is better to go for 70-75 % methanol

You may do the sequential extraction starting from Hexane, EtOAc or CH2Cl2 and finally with MeOH to take separate constituents. 

But by using MeOH you can get most of the constituents at once.

Best Wishes!!!

According to the type of compounds you need, there are many differences summarized in the following paper

Concept of standardization, extraction and pre phytochemical screening strategies for herbal drug

http://www.phytojournal.com/vol2Issue5/Issue_jan_2014/11.1.pdf

hydro-ethanolic extraction is better (preferably 95% ethanol)

Dear Abdulelah

As you see, the researcher use different way to extract the Phytochemical constituents,  all of them have the same purposes, and which of them is better?. It is not easy to say. Every one have our preferences. I agree with Mallique: use solvents increasing the polarity or extract directly with methanol and then partition technique with less polar solvents.  By other side, if you have to start to research a particular specie is better you look for previous research about the genus and take a look how they had worked.

The long list of articles provided by Dr BR Rajeshwar Rao is a sufficient information, I agreed with the views of these articles and Mr. C. Sharma suggestion, my view is also same that, Hydro-Ethanolic is suitable and safe solvent for plant extraction

Thank you so much for your help

Dear 

I agree with ethanol solvent is good for dry plant extraction

Already I expressed my views.

I agree with Mr. Chetan sharma and Mr. Punit Bhatt.

Generally, Methanol or water or Hydro-Methanol are used for extraction of dried herbal plant material.

i used six solvents for extraction of phytochemical constituent from dried/grined plant powder. Methanol was found to be best solvent followed by Ethanol, Acetone, E. Acetate, Chloroform and hexane.

Dear, All

Thank you so much for your help.

You can try organic solvents Such as Methanol (lower boiling point) or ethanol (somewhat higher boiling point), pure acetone or acetone/water mixtures.

Ethanol, Hydro-alcoholic, pure Acetone or Acetone/water mixtures, Hexane are best and safe in animal experimentation.

Use a polar and non-polar solvent. For non-polar compounds, hexane, benzene, petroleum ether, etc. For polar compounds, ethanol 40% and 70% can be used. It depends on what class of compounds you are studying. Methanol and 96% ethanol extracts all secondary and primary metabolites from plants.

You can use 80% methanol.

I think that you should try different types of solvents and see which one give you the best results .

Dear, All Thank you so much for your help.

rom my experiences in extractions methanol is the best alcoholic solvent for most phytochemical compounds and when calculating their quantities they are highest in methanolic extract comparing to the ethanolic. Safety should not be neglected, some traces of methanol remains with extract and in long term uses are not safe.The following factors should be considered when selecting a solvent for commercial extraction plant utilization:

• solvent power (selectivity);
• combability with local legislation about permitted solvent levels in the product - this is particularly important for food applications.
• boiling temperature - this should be low in order to facilitate removal of the solvent from the product;
• latent heat of vaporization;
• reactivity - the solvent should not react chemically with the extract, nor should it readily decompose;
• viscosity - must be low;
• stability to heat, oxygen and light;
• safety in use - the solvent should, if possible, be non-flammable and should not present a toxicity hazard to technicians or consumers; its disposal should not endanger the environment;
• the solvent should be available in substantial quantities;
• cost;
• suitability for re-use;
• compability with local legislation about permitted solvent levels in the product - this is particularly important for food applications

For polar compounds, you can use (Water, Methanol, and Ethanol)

For nonpolar compounds, you can use (Chloroform, Hexane, and Petroleum ether)

Use a polar and non-polar solvent. For non-polar compounds, hexane, benzene, petroleum ether, etc. For polar compounds, ethanol 40% and 70% can be used. It depends on what class of compounds you are studying. Methanol and 96% ethanol extracts all secondary and primary metabolites from plants.

For non-polar compounds, hexane, benzene, petroleum ether, etc.

For polar compounds, ethanol, methanol and distilled water can be used. It is totally depend on what class of compounds you are extracted. In ethanolic, methanolic and aquoes extracts, all the secondary and primary metabolites from plants are present.