Please refer to this thread:

https://www.researchgate.net/post/Can_anyone_suggest_free_tools_to_perform_QSAR

VEGA QSAR from

https://www.vegahub.eu/portfolio-item/vega-qsar/

This is one possibility:

https://chembench.mml.unc.edu/

You can use PaDEL or Dragon software.

http://www.yapcwsoft.com/dd/padeldescriptor/

http://www.talete.mi.it/products/dragon_description.htm

vega qsar is one of the best platform and also check following link for further reference

http://crdd.osdd.net/qsar.php

Hello

https://www.click2drug.org/