I already use 2%Glycerin as Plasticizers but all of my expandable films are broken by using 0.1 N HCl (pH=1.2) media.
I am preparing a sustained-release capsule
Dear Md. Abu Jar Gifari
Please explore Polysorbate 20, Hydroxypropyl cellulose, Liquid Sorbitol, Triethyl citrate, Polyethylene glycol 6000, etc. which may be useful in improving the elasticity of expandable films for oral drug delivery.
Thanks for your suggestion.
I already use Poly Vinyl Alcohol (PVA). But i didn’t get any improvement.
I Will follow that excipients for new Formulation
Try using Vitamin E TPGS
OK, Sir
Try to use sodium alginate to improve film elasticity alongside PVA
Dear, Sana Shafique
Thanks for your response. I will apply Sodium Alginate for my next formulation. It is available in our Laboratory
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