How important it is to search a new protein or addition of a few connections in a signaling pathways?

I am not popular for searching some new proteins, or saying I found xxxxy, xxxd, xxxf, but I want to know how searching a new protein or peptide can be valuable, when we already know thousands of...

31 December 2014 1,265 3 View

What is Hypoxia Inducible Factor and how does it regulate cancer growth?

I have come across this gene/protein recently and found it as jack of all trade, but i am new to this please add up its role in cancer progression and its immunological correlation if any.

08 September 2014 4,564 7 View

Why are immune cells not able to kill or destroy cancer stem cells?

06 July 2014 1,042 4 View

Can anyone suggest me the best article regarding histopathological grading of brain tumors specially glioblastoma?

I had few but not in details.

03 April 2014 1,095 5 View

Most of the biomarkers of GBM based on proteins are common to other cancer also (EGFR,VGEF,PTEN,MGMT etc). How can it be specific for glioma?

What is the most specific marker of glioblastoma. Where this biomarker science leaning toward?

31 December 2013 1,728 3 View

How does one process a tumor sample infected with a bacteria or virus?

Specially brain tumors where probability is higher.

09 October 2013 3,436 8 View

What is cancer stem cell and how it differ from ipluoripotent stem cells

There may be differences..

06 July 2013 6,617 5 View

How can antioxidants be toxic for both normal and transformed cells?

Antioxidants have shown toxicity to cells, even differential for cancer and normal cells.

11 December 2012 7,286 12 View

What are the suitable cell lines for studying cellular radiation response

Fibroblast, epithelial generally preffered

09 October 2012 9,915 4 View

How does oxidative stress play a role in the development and growth of cancer cells? What happens when we change the redox status?

Redox status play a role

04 May 2012 3,217 11 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View

Is it possible that Cancer cells could survive in heparinized blood for 48 hours?

Hi everyone, I am just wondering if we incubated 200 microliter of whole blood with 50 microliter of cancer cells(1bout 5000cells) do you think that cancer would survive for 48 hours?

23 February 2021 3,840 3 View

How to culture mouse pheochromocytoma cells (MPC)?

Hi Everyone, Has anyone here worked with MPC cell line? Any tips or tricks? I am just venturing into cell biology and any advice on this topic would be highly appreciated. Thank you so much. Niusha

22 February 2021 3,891 2 View

The PC12 cell line characteristics?

Hello dear scientists, Does the undifferentiated PC12 cell line in terms of chromosome characteristics, proliferation, and drug reactions have the characteristics of cancer cells? Where is it...

21 February 2021 8,945 3 View

What is the minimum number of exosomes/ml to have a good yield of total RNA for Illumina sequencing?

I am using IZON qEV2 columns to isolate exosomes from 100 ml of cancer cell conditioned medium. in NTA analysis I usually see concentration of 2x10^9 particles/ml. But when I proceed with this...

20 February 2021 6,879 3 View